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RBM24 stabilizes hepatitis B virus pregenomic RNA but inhibits core protein translation by targeting the terminal redundancy sequence

The terminal redundancy (TR) sequence of the 3.5-kb hepatitis B virus (HBV) RNA contains sites that govern many crucial functions in the viral life cycle, including polyadenylation, translation, RNA packaging, and DNA synthesis. In the present study, RNA-binding motif protein 24 (RBM24) is shown to...

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Detalles Bibliográficos
Autores principales: Yao, Yongxuan, Yang, Bo, Cao, Huang, Zhao, Kaitao, Yuan, Yifei, Chen, Yingshan, Zhang, Zhenhua, Wang, Yun, Pei, Rongjuan, Chen, Jizheng, Hu, Xue, Zhou, Yuan, Lu, Mengji, Wu, Chunchen, Chen, Xinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951808/
https://www.ncbi.nlm.nih.gov/pubmed/29760415
http://dx.doi.org/10.1038/s41426-018-0091-4