Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis

A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. UBF (upstream binding factor) is one of the main Pol I transcription factors located in the nucleolus that activates rRNA gene transcription. E2F7 is an...

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Detalles Bibliográficos
Autores principales: Coutts, Amanda S, Munro, Shonagh, La Thangue, Nicholas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951837/
https://www.ncbi.nlm.nih.gov/pubmed/29760477
http://dx.doi.org/10.1038/s41419-018-0529-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951837/
https://www.ncbi.nlm.nih.gov/pubmed/29760477
http://dx.doi.org/10.1038/s41419-018-0529-6

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