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Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis
A prerequisite for protein synthesis is the transcription of ribosomal rRNA genes by RNA polymerase I (Pol I), which controls ribosome biogenesis. UBF (upstream binding factor) is one of the main Pol I transcription factors located in the nucleolus that activates rRNA gene transcription. E2F7 is an...
Autores principales: | Coutts, Amanda S, Munro, Shonagh, La Thangue, Nicholas B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951837/ https://www.ncbi.nlm.nih.gov/pubmed/29760477 http://dx.doi.org/10.1038/s41419-018-0529-6 |
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