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CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22
The tumor suppressor gene CD82/KAI1 is a member of the tetraspanin superfamily and organizes various membrane-based processes. Mycobacterium tuberculosis (MTB) persists in host macrophages by interfering with phagolysosome biogenesis and inflammatory responses, but the role of CD82 in controlling th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951854/ https://www.ncbi.nlm.nih.gov/pubmed/29760437 http://dx.doi.org/10.1038/s12276-018-0091-4 |