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CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22

The tumor suppressor gene CD82/KAI1 is a member of the tetraspanin superfamily and organizes various membrane-based processes. Mycobacterium tuberculosis (MTB) persists in host macrophages by interfering with phagolysosome biogenesis and inflammatory responses, but the role of CD82 in controlling th...

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Detalles Bibliográficos
Autores principales: Koh, Hyun-Jung, Kim, Ye-Ram, Kim, Jae-Sung, Yun, Jin-Seung, Kim, Sojin, Kim, Sun Young, Jang, Kiseok, Yang, Chul-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951854/
https://www.ncbi.nlm.nih.gov/pubmed/29760437
http://dx.doi.org/10.1038/s12276-018-0091-4