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A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells

PURPOSE: Glioblastoma (GBM) is the commonest brain tumour in adults. A sub-population of cells within these tumours, known as cancer stem cells (CSCs), is thought to mediate their chemo-/radiotherapy resistance. CD133 is a cell surface marker that is used to identify and isolate GBM CSCs. However, i...

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Detalles Bibliográficos
Autores principales: Ahmed, Eroje M., Bandopadhyay, Gagori, Coyle, Beth, Grabowska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951876/
https://www.ncbi.nlm.nih.gov/pubmed/29492900
http://dx.doi.org/10.1007/s13402-018-0374-8