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Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells

The commonly used antimitotic chemotherapeutic agents such as taxol and vinblastine arrest cell cycle progression by disrupting mitotic spindles, and cause cancer cells to undergo apoptosis through ‘mitotic catastrophe’. The molecular mechanisms by which these drugs induce apoptosis and their releva...

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Detalles Bibliográficos
Autores principales: Qi, Chen, Wang, Xin, Shen, Zhirong, Chen, She, Yu, Hong, Williams, Noelle, Wang, Gelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951888/
https://www.ncbi.nlm.nih.gov/pubmed/29497138
http://dx.doi.org/10.1038/s41422-018-0018-6