Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma

The biological behavior of melanoma is unfavorable in the elderly when compared to young subjects. We hypothesized that differences in T-cell responses might underlie the distinct behavior of melanoma in young and old melanoma patients. Therefore, we investigated the circulating T-cell compartment o...

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Detalles Bibliográficos
Autores principales: van den Brom, Rob R. H., van der Geest, Kornelis S. M., Brouwer, Elisabeth, Hospers, Geke A. P., Boots, Annemieke M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899/
https://www.ncbi.nlm.nih.gov/pubmed/29546435
http://dx.doi.org/10.1007/s00262-018-2148-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899/
https://www.ncbi.nlm.nih.gov/pubmed/29546435
http://dx.doi.org/10.1007/s00262-018-2148-6

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