Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+ multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions

Natural killer (NK) cell-based immunotherapy is a promising novel approach to treat cancer. However, NK cell function has been shown to be potentially diminished by factors common in the tumor microenvironment (TME). In this study, we assessed the synergistic potential of antibody-dependent cell-med...

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Detalles Bibliográficos
Autores principales: Mahaweni, Niken M., Bos, Gerard M. J., Mitsiades, Constantine S., Tilanus, Marcel G. J., Wieten, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951903/
https://www.ncbi.nlm.nih.gov/pubmed/29500635
http://dx.doi.org/10.1007/s00262-018-2140-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951903/
https://www.ncbi.nlm.nih.gov/pubmed/29500635
http://dx.doi.org/10.1007/s00262-018-2140-1

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