Evolutionary instability of CUG-Leu in the genetic code of budding yeasts

The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the ‘universa...

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Detalles Bibliográficos
Autores principales: Krassowski, Tadeusz, Coughlan, Aisling Y., Shen, Xing-Xing, Zhou, Xiaofan, Kominek, Jacek, Opulente, Dana A., Riley, Robert, Grigoriev, Igor V., Maheshwari, Nikunj, Shields, Denis C., Kurtzman, Cletus P., Hittinger, Chris Todd, Rokas, Antonis, Wolfe, Kenneth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951914/
https://www.ncbi.nlm.nih.gov/pubmed/29760453
http://dx.doi.org/10.1038/s41467-018-04374-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951914/
https://www.ncbi.nlm.nih.gov/pubmed/29760453
http://dx.doi.org/10.1038/s41467-018-04374-7

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