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Evolutionary instability of CUG-Leu in the genetic code of budding yeasts
The genetic code used in nuclear genes is almost universal, but here we report that it changed three times in parallel during the evolution of budding yeasts. All three changes were reassignments of the codon CUG, which is translated as serine (in 2 yeast clades), alanine (1 clade), or the ‘universa...
Autores principales: | Krassowski, Tadeusz, Coughlan, Aisling Y., Shen, Xing-Xing, Zhou, Xiaofan, Kominek, Jacek, Opulente, Dana A., Riley, Robert, Grigoriev, Igor V., Maheshwari, Nikunj, Shields, Denis C., Kurtzman, Cletus P., Hittinger, Chris Todd, Rokas, Antonis, Wolfe, Kenneth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951914/ https://www.ncbi.nlm.nih.gov/pubmed/29760453 http://dx.doi.org/10.1038/s41467-018-04374-7 |
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