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Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression

This review summarizes the roles of CAFs in forming a “cancerized” fibrotic stroma favorable to tumor initiation and dissemination, in particular highlighting the functions of the extracellular matrix component hyaluronan (HA) in these processes. The structural complexity of the tumor and its host m...

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Detalles Bibliográficos
Autores principales: McCarthy, James B., El-Ashry, Dorraya, Turley, Eva A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951929/
https://www.ncbi.nlm.nih.gov/pubmed/29868579
http://dx.doi.org/10.3389/fcell.2018.00048