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Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression
This review summarizes the roles of CAFs in forming a “cancerized” fibrotic stroma favorable to tumor initiation and dissemination, in particular highlighting the functions of the extracellular matrix component hyaluronan (HA) in these processes. The structural complexity of the tumor and its host m...
Autores principales: | McCarthy, James B., El-Ashry, Dorraya, Turley, Eva A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951929/ https://www.ncbi.nlm.nih.gov/pubmed/29868579 http://dx.doi.org/10.3389/fcell.2018.00048 |
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