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Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

Autophagy removes both functional and damaged intracellular macromolecules from cells via lysosomal degradation. Three autophagic mechanisms, namely macroautophagy, chaperone-mediated autophagy (CMA), and microautophagy, have been described in mammals. Studies in experimental systems have found macr...

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Detalles Bibliográficos
Autores principales: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952035/
https://www.ncbi.nlm.nih.gov/pubmed/29867441
http://dx.doi.org/10.3389/fnagi.2018.00130