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Automated Fragmentation QM/MM Calculation of NMR Chemical Shifts for Protein-Ligand Complexes
In this study, the automated fragmentation quantum mechanics/molecular mechanics (AF-QM/MM) method was applied for NMR chemical shift calculations of protein-ligand complexes. In the AF-QM/MM approach, the protein binding pocket is automatically divided into capped fragments (within ~200 atoms) for...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952040/ https://www.ncbi.nlm.nih.gov/pubmed/29868556 http://dx.doi.org/10.3389/fchem.2018.00150 |