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MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy

Temozolomide (TMZ) is one of the most commonly used drugs for the clinical treatment of glioblastomas. However, it has been reported that treatment with TMZ can induce autophagy, which leads to tumor resistance and increases the survival of tumor cells. MicroRNA-30a (miR-30a) has been found to have...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Huang, He, Peng, Renjun, Ding, Xiping, Jiang, Bing, Yuan, Xianrui, Xi, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952084/
https://www.ncbi.nlm.nih.gov/pubmed/29805498
http://dx.doi.org/10.3892/etm.2018.6007