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Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine

Current evidence supports a protective role for virus-neutralizing antibodies in immunity against hepatitis C virus (HCV) infection. Many cross-neutralizing monoclonal antibodies have been identified. These antibodies have been shown to provide protection or to clear infection in animal models. Prev...

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Detalles Bibliográficos
Autores principales: Law, John L. M., Logan, Michael, Wong, Jason, Kundu, Juthika, Hockman, Darren, Landi, Amir, Chen, Chao, Crawford, Kevin, Wininger, Mark, Johnson, Janelle, Mesa Prince, Catalina, Dudek, Elzbieta, Mehta, Ninad, Tyrrell, D. Lorne, Houghton, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952160/
https://www.ncbi.nlm.nih.gov/pubmed/29540595
http://dx.doi.org/10.1128/JVI.02141-17