Cargando…

Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules

[Image: see text] The mucoid biofilm mode of growth of Pseudomonas aeruginosa (P. aeruginosa) in the lungs of cystic fibrosis patients makes eradication of infections with antibiotic therapy very difficult. The lipopeptide antibiotics polymyxin B and colistin are currently the last-resort therapies...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider-Futschik, Elena K., Paulin, Olivia K. A., Hoyer, Daniel, Roberts, Kade D., Ziogas, James, Baker, Mark A., Karas, John, Li, Jian, Velkov, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952261/
https://www.ncbi.nlm.nih.gov/pubmed/29566483
http://dx.doi.org/10.1021/acsinfecdis.7b00238