BC RNA Mislocalization in the Fragile X Premutation

Fragile X premutation disorder is caused by CGG triplet repeat expansions in the 5′ untranslated region of FMR1 mRNA. The question of how expanded CGG repeats cause disease is a subject of continuing debate. Our work indicates that CGG-repeat structures compete with regulatory BC1 RNA for access to...

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Detalles Bibliográficos
Autores principales: Muslimov, Ilham A., Eom, Taesun, Iacoangeli, Anna, Chuang, Shih-Chieh, Hukema, Renate K., Willemsen, Rob, Stefanov, Dimitre G., Wong, Robert K. S., Tiedge, Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952321/
https://www.ncbi.nlm.nih.gov/pubmed/29766042
http://dx.doi.org/10.1523/ENEURO.0091-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952321/
https://www.ncbi.nlm.nih.gov/pubmed/29766042
http://dx.doi.org/10.1523/ENEURO.0091-18.2018

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