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Cyanidin-3-glucoside Alleviates 4-Hydroxyhexenal-Induced NLRP3 Inflammasome Activation via JNK-c-Jun/AP-1 Pathway in Human Retinal Pigment Epithelial Cells

Recently, the NLRP3 inflammasome activation in the eyes has been known to be associated with the pathogenesis of age-related macular degeneration. The aim of this study was to investigate the protective effects of cyanidin-3-glucoside (C3G), an important anthocyanin with great potential for preventi...

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Detalles Bibliográficos
Autores principales: Jin, Xiaolu, Wang, Chengtao, Wu, Wei, Liu, Tingting, Ji, Baoping, Zhou, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952446/
https://www.ncbi.nlm.nih.gov/pubmed/29854843
http://dx.doi.org/10.1155/2018/5604610