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S-allylcysteine suppresses ovarian cancer cell proliferation by DNA methylation through DNMT1

BACKGROUND: The anti-tumor effects of S-allylcysteine (SAC), a water-soluble garlic derivative, on human ovarian cancer cells have been previous studied in vitro and in vivo models but the precise epigenetic molecular mechanisms are still unclear. This study aimed to investigate the epigenetic mecha...

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Detalles Bibliográficos
Autores principales: Xu, Yasi, Su, Dan, Zhu, Lucheng, Zhang, Shirong, Ma, Shenglin, Wu, Kan, Yuan, Qiang, Lin, Nengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952516/
https://www.ncbi.nlm.nih.gov/pubmed/29759079
http://dx.doi.org/10.1186/s13048-018-0412-1