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Intestinal Permeability of Artesunate-Loaded Solid Lipid Nanoparticles Using the Everted Gut Method

BACKGROUND: Artesunate is one of the most potent, rapidly acting and therapeutically versatile antimalarial drugs. Its efficacy is hampered by poor aqueous solubility and stability resulting in low oral bioavailability. Recent efforts to nanoformulate artesunate have shown great potential of improvi...

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Detalles Bibliográficos
Autores principales: Masiiwa, Wadzanayi L., Gadaga, Louis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952556/
https://www.ncbi.nlm.nih.gov/pubmed/29854465
http://dx.doi.org/10.1155/2018/3021738