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Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial

BACKGROUND: Pyronaridine–artesunate is a novel artemisinin-based combination therapy. The efficacy and safety of pyronaridine–artesunate were compared with artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children. METHODS: This phase III open-label randomi...

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Detalles Bibliográficos
Autores principales: Roth, Johanna M., Sawa, Patrick, Makio, Nicodemus, Omweri, George, Osoti, Victor, Okach, Selpha, Choy, Felix, Schallig, Henk D. F. H., Mens, Pètra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952621/
https://www.ncbi.nlm.nih.gov/pubmed/29764419
http://dx.doi.org/10.1186/s12936-018-2340-3