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Platelets activated by the anti-β2GPI/β2GPI complex release microRNAs to inhibit migration and tube formation of human umbilical vein endothelial cells

BACKGROUND: Patients with anti-β2GPI antibodies display significantly higher platelet activation/aggregation and vascular endothelial cell damage. The mechanism underlying the correlation between platelet activation, vascular endothelial cell dysfunctions and anti-β2GPI antibodies remains unknown. M...

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Detalles Bibliográficos
Autores principales: Zhang, Yanfen, Zhang, Wenjing, Zha, Caijun, Liu, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952642/
https://www.ncbi.nlm.nih.gov/pubmed/29785186
http://dx.doi.org/10.1186/s11658-018-0091-3