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Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury

BACKGROUND: Acute neurological insults caused by infection, systemic inflammation, ischemia, or traumatic injury are often associated with breakdown of the blood-brain barrier (BBB) followed by infiltration of peripheral immune cells, cytotoxic proteins, and water. BBB breakdown and extravasation of...

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Detalles Bibliográficos
Autores principales: Piro, Justin R., Suidan, Georgette L., Quan, Jie, Pi, YeQing, O’Neill, Sharon M., Ilardi, Marissa, Pozdnyakov, Nikolay, Lanz, Thomas A., Xi, Hualin, Bell, Robert D., Samad, Tarek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952841/
https://www.ncbi.nlm.nih.gov/pubmed/29759062
http://dx.doi.org/10.1186/s12974-018-1166-9