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Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

BACKGROUND: Microglial activation contributes to the neuropathology associated with chronic alcohol exposure and withdrawal, including the expression of inflammatory and anti-inflammatory genes. In the current study, we examined the transcriptome of primary rat microglial cells following incubation...

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Detalles Bibliográficos
Autores principales: Kalinin, Sergey, González-Prieto, Marta, Scheiblich, Hannah, Lisi, Lucia, Kusumo, Handojo, Heneka, Michael T., Madrigal, Jose L. M., Pandey, Subhash C., Feinstein, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952855/
https://www.ncbi.nlm.nih.gov/pubmed/29759078
http://dx.doi.org/10.1186/s12974-018-1184-7