Cargando…

Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

BACKGROUND: Microglial activation contributes to the neuropathology associated with chronic alcohol exposure and withdrawal, including the expression of inflammatory and anti-inflammatory genes. In the current study, we examined the transcriptome of primary rat microglial cells following incubation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalinin, Sergey, González-Prieto, Marta, Scheiblich, Hannah, Lisi, Lucia, Kusumo, Handojo, Heneka, Michael T., Madrigal, Jose L. M., Pandey, Subhash C., Feinstein, Douglas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952855/ https://www.ncbi.nlm.nih.gov/pubmed/29759078 http://dx.doi.org/10.1186/s12974-018-1184-7

Ejemplares similares

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
por: Friker, Lea L., et al.
Publicado: (2020)

LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation
por: Reid, Kyle M., et al.
Publicado: (2023)

VIP Enhances Phagocytosis of Fibrillar Beta-Amyloid by Microglia and Attenuates Amyloid Deposition in the Brain of APP/PS1 Mice
por: Song, Min, et al.
Publicado: (2012)

Neuroimmune and epigenetic involvement in adolescent binge ethanol‐induced loss of basal forebrain cholinergic neurons: Restoration with voluntary exercise
por: Vetreno, Ryan P., et al.
Publicado: (2019)

Truncated and modified amyloid-beta species
por: Kummer, Markus P, et al.
Publicado: (2014)

Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides(i)
por: Fleisher-Berkovich, Sigal, et al.
Publicado: (2010)

TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer’s Disease
por: La Rosa, Francesca, et al.
Publicado: (2023)

Traumatic Brain Injury, Microglia, and Beta Amyloid
por: Mannix, Rebekah C., et al.
Publicado: (2012)

Neuronal Death Induced by Nanomolar Amyloid β Is Mediated by Primary Phagocytosis of Neurons by Microglia
por: Neniskyte, Urte, et al.
Publicado: (2011)

Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid
por: Rubio-Araiz, Ana, et al.
Publicado: (2018)

Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis
por: Krishnan, Harish R., et al.
Publicado: (2022)

Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates
por: Clark, Gretchen T., et al.
Publicado: (2022)

Aging and sex: Impact on microglia phagocytosis
por: Yanguas‐Casás, Natalia, et al.
Publicado: (2020)

Fluoxetine Potentiates Phagocytosis and Autophagy in Microglia
por: Park, Sung Hee, et al.
Publicado: (2021)

Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
por: Scheiblich, Hannah, et al.
Publicado: (2021)

Increased tauopathy drives microglia-mediated clearance of beta-amyloid
por: Chen, Wesley, et al.
Publicado: (2016)

The Role of Aldose Reductase in Beta-Amyloid-Induced Microglia Activation
por: Huang, Yu-Kai, et al.
Publicado: (2022)

Phagocytosis of Microglia in the Central Nervous System Diseases
por: Fu, Ruying, et al.
Publicado: (2014)

Comparative Review of Microglia and Monocytes in CNS Phagocytosis
por: Andoh, Megumi, et al.
Publicado: (2021)

Regulation of microglia phagocytosis and potential involvement of exercise
por: Li, Congqin, et al.
Publicado: (2022)

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
por: Sondag, Cindy M, et al.
Publicado: (2009)

Protective Role of Microglia on Neuronal Survival after Exposure to Amyloid Beta
por: Lee, Sunjun, et al.
Publicado: (2022)

Microglia use TAM receptors to detect and engulf amyloid beta plaques
por: Huang, Youtong, et al.
Publicado: (2021)

Intravenous Immunglobulin Binds Beta Amyloid and Modifies Its Aggregation, Neurotoxicity and Microglial Phagocytosis In Vitro
por: Cattepoel, Susann, et al.
Publicado: (2013)

Differential Regulation of Adhesion and Phagocytosis of Resting and Activated Microglia by Dopamine
por: Fan, Yang, et al.
Publicado: (2018)

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
por: Krabbe, Grietje, et al.
Publicado: (2013)

Calreticulin and Galectin-3 Opsonise Bacteria for Phagocytosis by Microglia
por: Cockram, Tom O. J., et al.
Publicado: (2019)

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation
por: Caldeira, Cláudia, et al.
Publicado: (2017)

Transcriptional signature in microglia associated with Aβ plaque phagocytosis
por: Grubman, Alexandra, et al.
Publicado: (2021)

Microglia in Alzheimer’s disease: Local heroes!
por: Villacampa, Nàdia, et al.
Publicado: (2020)

Primary Phagocytosis of Neurons by Inflamed Microglia: Potential Roles in Neurodegeneration
por: Neher, Jonas J., et al.
Publicado: (2012)

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
por: Sierra, Amanda, et al.
Publicado: (2013)

Protocol for assessing phagocytosis activity in cultured primary murine microglia
por: Layman, Elsie, et al.
Publicado: (2022)

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology
por: Borggrewe, Malte, et al.
Publicado: (2021)

SRPK2 Expression and Beta-Amyloid Accumulation Are Associated With BV2 Microglia Activation
por: Tian, Ziqi, et al.
Publicado: (2022)

Vaccination with (1–11)E2 in alum efficiently induces an antibody response to β-amyloid without affecting brain β-amyloid load and microglia activation in 3xTg mice
por: Mantile, Francesca, et al.
Publicado: (2019)

Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes
por: Kim, Dong Won, et al.
Publicado: (2022)

M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia
por: Smith, Amy M, et al.
Publicado: (2013)

Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
por: Das, Rashmi, et al.
Publicado: (2020)

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome
por: Diaz-Aparicio, Irune, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lf9mcbnso5t0dvglth71lv1rcr