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Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia

Oxysterols (OHC) are biologically active cholesterol metabolites circulating in plasma that may be formed enzymatically (e.g. 24S-OHC, 25-OHC and 27-OHC) or by autoxidative mechanisms (e.g. 7-ketocholesterol, 7β-OHC and 25-OHC). Oxysterols are more soluble than cholesterol and are reported to exert...

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Detalles Bibliográficos
Autores principales: Dias, Irundika H.K., Milic, Ivana, Lip, Gregory Y.H., Devitt, Andrew, Polidori, M. Cristina, Griffiths, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952874/
https://www.ncbi.nlm.nih.gov/pubmed/29501047
http://dx.doi.org/10.1016/j.redox.2018.02.014