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Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia
Oxysterols (OHC) are biologically active cholesterol metabolites circulating in plasma that may be formed enzymatically (e.g. 24S-OHC, 25-OHC and 27-OHC) or by autoxidative mechanisms (e.g. 7-ketocholesterol, 7β-OHC and 25-OHC). Oxysterols are more soluble than cholesterol and are reported to exert...
Autores principales: | Dias, Irundika H.K., Milic, Ivana, Lip, Gregory Y.H., Devitt, Andrew, Polidori, M. Cristina, Griffiths, Helen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952874/ https://www.ncbi.nlm.nih.gov/pubmed/29501047 http://dx.doi.org/10.1016/j.redox.2018.02.014 |
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