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A potential gliovascular mechanism for microglial activation: differential phenotypic switching of microglia by endothelium versus astrocytes

BACKGROUND: Activation of microglia can result in phenotypic and functional diversity. However, the pathways that trigger different states of microglial activation remain to be fully understood. Here, we hypothesized that after injury, astrocytes and endothelium may contribute to a gliovascular swit...

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Detalles Bibliográficos
Autores principales: Xing, Changhong, Li, Wenlu, Deng, Wenjun, Ning, MingMing, Lo, Eng H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952884/
https://www.ncbi.nlm.nih.gov/pubmed/29764475
http://dx.doi.org/10.1186/s12974-018-1189-2