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Age-dependent regulation of antioxidant genes by p38α MAPK in the liver

p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elucidate the mechanism(s) involved and the age-related...

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Detalles Bibliográficos
Autores principales: Pérez, Salvador, Rius-Pérez, Sergio, Tormos, Ana M., Finamor, Isabela, Nebreda, Ángel R., Taléns-Visconti, Raquel, Sastre, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952885/
https://www.ncbi.nlm.nih.gov/pubmed/29567616
http://dx.doi.org/10.1016/j.redox.2018.02.017