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Evaluating approaches to find exon chains based on long reads

Transcript prediction can be modeled as a graph problem where exons are modeled as nodes and reads spanning two or more exons are modeled as exon chains. Pacific Biosciences third-generation sequencing technology produces significantly longer reads than earlier second-generation sequencing technolog...

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Detalles Bibliográficos
Autores principales: Kuosmanen, Anna, Norri, Tuukka, Mäkinen, Veli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952954/
https://www.ncbi.nlm.nih.gov/pubmed/28069635
http://dx.doi.org/10.1093/bib/bbw137