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AKT-independent activation of p38 MAP kinase promotes vascular calcification

Vascular calcification is prevalent in patients with atherosclerosis, and oxidative stress promotes pathogenesis of atherosclerosis. We have previously reported that activation of AKT by oxidative stress induces vascular calcification. Using sodium dichloroacetate (DCA), a previously reported small...

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Detalles Bibliográficos
Autores principales: Yang, Youfeng, Sun, Yong, Chen, Jianye, Bradley, Wayne E., Dell’Italia, Louis J., Wu, Hui, Chen, Yabing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952999/
https://www.ncbi.nlm.nih.gov/pubmed/29495001
http://dx.doi.org/10.1016/j.redox.2018.02.009