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Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy

Cellular senescence is characterized by irreversible growth arrest incurred through either replicative exhaustion or by pro-oncogenic cellular stressors (radioactivity, oxidative stress, oncogenic activation). The enrichment of senescent cells in tissues with age has been associated with tissue dysh...

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Detalles Bibliográficos
Autores principales: Masaldan, Shashank, Clatworthy, Sharnel A.S., Gamell, Cristina, Smith, Zoe M., Francis, Paul S., Denoyer, Delphine, Meggyesy, Peter M., Fontaine, Sharon La, Cater, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953000/
https://www.ncbi.nlm.nih.gov/pubmed/29579719
http://dx.doi.org/10.1016/j.redox.2018.03.007