An enantioselective artificial Suzukiase based on the biotin–streptavidin technology

Introduction of a biotinylated monophosphine palladium complex within streptavidin affords an enantioselective artificial Suzukiase. Site-directed mutagenesis allowed the optimization of the activity and the enantioselectivity of this artificial metalloenzyme. A variety of atropisomeric biaryls were...

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Detalles Bibliográficos
Autores principales: Chatterjee, Anamitra, Mallin, Hendrik, Klehr, Juliane, Vallapurackal, Jaicy, Finke, Aaron D., Vera, Laura, Marsh, May, Ward, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953008/
https://www.ncbi.nlm.nih.gov/pubmed/29896353
http://dx.doi.org/10.1039/c5sc03116h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953008/
https://www.ncbi.nlm.nih.gov/pubmed/29896353
http://dx.doi.org/10.1039/c5sc03116h

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