Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes

Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in diabetes. Epigenetic mechanisms, such as histone acetylation, emerged as important regulators of gene expression in cardiovascular disorders. Since thei...

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Detalles Bibliográficos
Autores principales: Manea, Simona-Adriana, Antonescu, Mihaela-Loredana, Fenyo, Ioana Madalina, Raicu, Monica, Simionescu, Maya, Manea, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953221/
https://www.ncbi.nlm.nih.gov/pubmed/29587244
http://dx.doi.org/10.1016/j.redox.2018.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953221/
https://www.ncbi.nlm.nih.gov/pubmed/29587244
http://dx.doi.org/10.1016/j.redox.2018.03.011

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