The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission

The accumulation of uremic toxins in chronic kidney disease (CKD) induces inflammation, oxidative stress and endothelial dysfunction, which is a key step in atherosclerosis. Accumulating evidence indicates increased mitochondrial fission is a contributing mechanism for impaired endothelial function....

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Detalles Bibliográficos
Autores principales: Huang, Mengjie, Wei, Ribao, Wang, Yang, Su, Tingyu, Li, Ping, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953222/
https://www.ncbi.nlm.nih.gov/pubmed/29573704
http://dx.doi.org/10.1016/j.redox.2018.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953222/
https://www.ncbi.nlm.nih.gov/pubmed/29573704
http://dx.doi.org/10.1016/j.redox.2018.03.010

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