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Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression

Histological assessments of synovial tissues from patients with failed CoCr alloy hip prostheses demonstrate extensive infiltration and accumulation of macrophages, often loaded with large quantities of particulate debris. The resulting adverse reaction to metal debris (ARMD) frequently leads to ear...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Yang, Junyao, Nyga, Agata, Ehteramyan, Mazdak, Moraga, Ana, Wu, Yuanhao, Zeng, Lingfang, Knight, Martin M., Shelton, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953279/
https://www.ncbi.nlm.nih.gov/pubmed/29649639
http://dx.doi.org/10.1016/j.actbio.2018.03.054