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Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice
Mutations in the filaggrin gene (Flg) are associated with increased systemic levels of Th17 cells and increased IL-17A production following antigen exposure in both humans and mice. In addition to Th17 cells, γδ T cells can produce IL-17A. The differentiation of γδ T cells to either IFNγ or IL-17A-p...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953325/ https://www.ncbi.nlm.nih.gov/pubmed/29867965 http://dx.doi.org/10.3389/fimmu.2018.00988 |