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Phase I Randomized Study of a Tetravalent Dengue Purified Inactivated Vaccine in Healthy Adults from Puerto Rico

The safety and immunogenicity of four adjuvanted formulations of an investigational tetravalent dengue purified inactivated vaccine (DPIV) were evaluated in a predominantly dengue-primed population in Puerto Rico. In this placebo-controlled, randomized, observer-blind, phase I trial, 100 healthy adu...

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Detalles Bibliográficos
Autores principales: Diaz, Clemente, Lin, Leyi, Martinez, Luis J., Eckels, Kenneth H., Campos, Maribel, Jarman, Richard G., De La Barrera, Rafael, Lepine, Edith, Toussaint, Jean-François, Febo, Irma, Innis, Bruce L., Thomas, Stephen J., Schmidt, Alexander C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953365/
https://www.ncbi.nlm.nih.gov/pubmed/29512481
http://dx.doi.org/10.4269/ajtmh.17-0627