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Molecular and clinical characterization of PTPN2 expression from RNA-seq data of 996 brain gliomas

BACKGROUND: Immune checkpoint inhibitors have been shown to promote antitumor immunity and achieve durable tumor remissions. However, certain tumors are refractory to current immunotherapy. These negative results encouraged us to uncover other therapeutic targets and strategies. PTPN2 (protein tyros...

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Detalles Bibliográficos
Autores principales: Wang, Peng-fei, Cai, Hong-qing, Zhang, Chuan-bao, Li, Yan-Michael, Liu, Xiang, Wan, Jing-hai, Jiang, Tao, Li, Shou-wei, Yan, Chang-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953404/
https://www.ncbi.nlm.nih.gov/pubmed/29764444
http://dx.doi.org/10.1186/s12974-018-1187-4