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Molecular and clinical characterization of PTPN2 expression from RNA-seq data of 996 brain gliomas
BACKGROUND: Immune checkpoint inhibitors have been shown to promote antitumor immunity and achieve durable tumor remissions. However, certain tumors are refractory to current immunotherapy. These negative results encouraged us to uncover other therapeutic targets and strategies. PTPN2 (protein tyros...
Autores principales: | Wang, Peng-fei, Cai, Hong-qing, Zhang, Chuan-bao, Li, Yan-Michael, Liu, Xiang, Wan, Jing-hai, Jiang, Tao, Li, Shou-wei, Yan, Chang-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953404/ https://www.ncbi.nlm.nih.gov/pubmed/29764444 http://dx.doi.org/10.1186/s12974-018-1187-4 |
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