Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia

Microvascular endothelial cells play a pivotal role in the pathogenesis of sepsis-induced inflammatory responses and multiple organ failure. Therefore, they represent an important target for pharmacological intervention in the treatment of sepsis. Glucocorticosteroids were widely used in the treatme...

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Detalles Bibliográficos
Autores principales: Li, Ranran, Kowalski, Piotr S., Morselt, Henriëtte W. M., Schepel, Ilona, Jongman, Rianne M., Aslan, Adnan, Ruiters, Marcel H. J., Zijlstra, Jan G., Molema, Grietje, van Meurs, Matijs, Kamps, Jan A. A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953446/
https://www.ncbi.nlm.nih.gov/pubmed/29763440
http://dx.doi.org/10.1371/journal.pone.0196976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953446/
https://www.ncbi.nlm.nih.gov/pubmed/29763440
http://dx.doi.org/10.1371/journal.pone.0196976

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