Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G(13)

The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein G(i) in both canonical and noncanonical forms of signaling. Other G proteins, while not specifically utilized by Smo, may nonetheless provide access to...

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Detalles Bibliográficos
Autores principales: Guo, Xueshui, Riobo-Del Galdo, Natalia A., Kim, Eun Ji, Grant, Gregory R., Manning, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953476/
https://www.ncbi.nlm.nih.gov/pubmed/29763457
http://dx.doi.org/10.1371/journal.pone.0197442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953476/
https://www.ncbi.nlm.nih.gov/pubmed/29763457
http://dx.doi.org/10.1371/journal.pone.0197442

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