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Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G(13)
The Hedgehog family of morphogens has long been known to utilize, through the 7-transmembrane protein Smoothened (Smo), the heterotrimeric G protein G(i) in both canonical and noncanonical forms of signaling. Other G proteins, while not specifically utilized by Smo, may nonetheless provide access to...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953476/ https://www.ncbi.nlm.nih.gov/pubmed/29763457 http://dx.doi.org/10.1371/journal.pone.0197442 |