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Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling
The HMG-CoA reductase inhibitors, statins, have been used as lipid lowering drugs for decades and several epidemiological studies suggest statin usage correlates with a decreased incidence of cancer specific mortality in patients. However, the mechanism of this mortality benefit remains unclear. Her...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953490/ https://www.ncbi.nlm.nih.gov/pubmed/29763460 http://dx.doi.org/10.1371/journal.pone.0197422 |