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Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia

BACKGROUND: There is evidence that maternal genotypes in folate-related genes are associated with pediatric acute lymphoblastic leukemia (ALL) independent of offspring genotype. We evaluated the relationship between maternal genotypes in methionine synthase (MTR) and DNA methylation status in ALL to...

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Detalles Bibliográficos
Autores principales: Schraw, Jeremy M., Yiu, Teresa T., Lupo, Philip J., Tsavachidis, Spiridon, Rau, Rachel, Bondy, Melissa L., Rabin, Karen R., Shen, Lanlan, Scheurer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953491/
https://www.ncbi.nlm.nih.gov/pubmed/29763473
http://dx.doi.org/10.1371/journal.pone.0197408