IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

Host factors restricting the transmission of respiratory viruses are poorly characterized. We analyzed the contribution of type I and type III interferon (IFN) using a mouse model in which the virus is selectively administered to the upper airways, mimicking a natural respiratory virus infection. Mi...

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Detalles Bibliográficos
Autores principales: Klinkhammer, Jonas, Schnepf, Daniel, Ye, Liang, Schwaderlapp, Marilena, Gad, Hans Henrik, Hartmann, Rune, Garcin, Dominique, Mahlakõiv, Tanel, Staeheli, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953542/
https://www.ncbi.nlm.nih.gov/pubmed/29651984
http://dx.doi.org/10.7554/eLife.33354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953542/
https://www.ncbi.nlm.nih.gov/pubmed/29651984
http://dx.doi.org/10.7554/eLife.33354

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