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Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner

Local administration of toll-like receptor 9 (TLR9), agonist cytidine-phosphate-guanosine oligodeoxynucleotide (CpG ODNs), and CD40 ligand (CD40L) can decrease ligature-induced periodontal inflammation and bone loss in wild type (WT) mouse. OBJECTIVE: This study aimed to explore whether such effect...

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Detalles Bibliográficos
Autores principales: Zhao, Qian, Hu, Yang, Deng, Shu, Yu, Pei, Chen, Bowen, Wang, Zuomin, Han, Xiaozhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953564/
https://www.ncbi.nlm.nih.gov/pubmed/29791566
http://dx.doi.org/10.1590/1678-7757-2017-0451