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Detection of HIV-1-Specific Gastrointestinal Tissue Resident CD8(+) T-cells in Chronic Infection

Tissue-resident memory (T(RM)) CD8(+) T-cells are non-recirculating, long-lived cells housed in tissues that can confer protection against mucosal pathogens. HIV-1 is a mucosal pathogen and the gastrointestinal tract is an important site of viral pathogenesis and transmission. Thus, CD8(+) T(RM) cel...

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Detalles Bibliográficos
Autores principales: Kiniry, Brenna E., Li, Shengbin, Ganesh, Anupama, Hunt, Peter W., Somsouk, Ma, Skinner, Pamela J., Deeks, Steven G., Shacklett, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953759/
https://www.ncbi.nlm.nih.gov/pubmed/29139476
http://dx.doi.org/10.1038/mi.2017.96