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Insights from the Molecular Modelling and Docking Analysis of AIF-NLS complex to infer Nuclear Translocation of the Protein

Apoptosis Inducing Factor protein has a dual role depending on its localization in mitochondrion (energy production) and nucleus (induces apoptosis). Cell damage transports this protein to nucleus which otherwise favors mitochondrion. The alteration of Nuclear Localisation Signal tags could aid nucl...

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Detalles Bibliográficos
Autores principales: Srivaths, Akash, Ramanathan, Shyam, Sakthivel, Seethalakshmi, Habeeb, SKM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953855/
https://www.ncbi.nlm.nih.gov/pubmed/29785072
http://dx.doi.org/10.6026/97320630014132